欧宝体育app
请神回复为您讲课GLP-1 多巴胺受体着急剂的开发。胰高血糖素样肽-1(GLP-1)肾上腺素受体激动得剂的布置更多的适应环境症为2型血糖值高的和糖尿病症。GLP-1 receptor agonists are now used for the treatment of type 2 diabetes and obesity.回首过去以前,从看见GLP-1是胰高血糖素原经酶促裂解后引起的,再到Exendent-4 的看见。Looking back, GLP-1 was found to be a cleavage product of proglucagon processing.Exendent-4 是GLP-1发展前景世上的一些根本的冲刺。Exendent-4就是一种对GLP-1感觉具备着清凉用但能抵挡DPP-4可降解的肽。司美格鲁肽是各国第一款服食的GLP-1感觉清凉剂。A key breakthrough came from the discovery of exendent-4. Exendent-4 is a peptide with agonistic properties at the GLP-1 receptor but resistance to degradation by DPP-4.Semiglutide, the first oral GLP-1 receptor agonist marked the next milestone.